Research Clinical Trials

At UMass Memorial Cancer Center of Excellence in Worcester, MA, we work in partnership with the University of Massachusetts Medical School to research new treatments for cancer. UMass Memorial is at the forefront of some of the nation’s most promising research and treatment programs. Through our Cancer Center Clinical Research Office, we perform breakthrough research and clinical trials to improve treatment and your quality of life.

Brain Cancer Trials Underway

BrUOG 244 PPX
H-14764: PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study
INVESTIGATOR: Shakeeb Yunus, MD
SPONSOR: Brown University Oncology Research Group

BrUOG 244 at clinicaltrials.gov 
Celldex ACT IV
CDX110-04 An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The “ACT IV” Study)
INVESTIGATOR: Shakeeb Yunus, MD
SPONSOR: Celldex Therapeutics

Celldex ACT IV at clinicaltrials.gov 


Learn more about research and other clinical trials underway at the UMass Memorial Cancer Center of Excellence

To learn more about clinical trials and cancer research,
call 508-856-3216 or email cancer.research@umassmed.edu.