Discovering and Delivering Compassionate, Coordinated Care
At UMass Memorial Cancer Center of Excellence in Worcester, MA, we work in partnership with the University of Massachusetts Medical School to research new treatments for cancer. UMass Memorial is at the forefront of some of the nation’s most promising research and treatment programs. Through our Cancer Center Clinical Research Office (CRO), we perform breakthrough research and clinical trials to improve treatment and your quality of life.
Leukemia Trials Underway
Cellerant CLT-008
A Phase I/II Trial of CLT -008 Myeloid Progenitor Cells in Patients Receiving Post-Remission Therapy for High Risk Leukemia or Myelodysplasia
INVESTIGATOR: Jan Cerny, MD, PhD
SPONSOR: Cellerant Therapeutics, Inc
Cellerant CLT-008 at clinicaltrials.gov
Southwest Oncology Group
SWOG 1117
A Randomized Phase II Study of Azacitidine in Combination with Lenalidomide (NSC-703813) vs. Azacitidine Alone vs. Azacitidine in Combination with Vorinostat (NSC-701852) for Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)
INVESTIGATOR: Muthalagu Ramanathan, MD
SPONSOR: Southwest Oncology Group
SWOG 1117 at clinicaltrials.gov
Eastern Cooperative Oncology Group (ECOG)
ECOG 2905
Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid®) Alone and in Combination with Epoetin Alfa (Procrit®) in Subjects with Low- or Intermediate-1 Risk MDS and Symptomatic Anemia
INVESTIGATOR: Muthalagu Ramanathan, MD
SPONSOR: Eastern Cooperative Oncology Group (ECOG)
ECOG 2905 at clinicaltrials.gov
University of Massachusetts Medical School
Blood & Bone Marrow Collection (UM200901)
Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth in Patients with Malignancy or Hematologic Disorders Malignancy or Hematologic Disorders
INVESTIGATOR: Jan Cerny, MD, PhD
SPONSOR: University of Massachusetts Medical School
UM200901 at clinicaltrials.gov
Bristol-Myers Squibb Company
Simplicity CA180330
5 year Prospective Studying Interventions for Managing Patients with Chronic Myeloid Leukemia in Chronic Phase
INVESTIGATOR: Jan Cerny, MD, PhD
SPONSOR: Bristol-Myers Squibb Company
Simplicity CA180330 at clinicaltrials.gov
GSK WT1-AS01B-AML-002 (111727)
Study of GSK2130579 a Tumor-Antigen-Specific Cancer Immunotherapeutic in Adult Acute Myeloid Leukemia Patients with a Suboptimal Clinical Response to Induction Chemotherapy
INVESTIGATOR: Rajneesh Nath, MD
SPONSOR: GlaxoSmithKline Pharmaceutical
GSK WT1-AS01B-AML-002 at clinicaltrials.gov
Learn more about research and other clinical trials underway at the UMass Memorial Cancer Center of Excellence.
To learn more about clinical trials and cancer research, call 508-856-3216 or email cancer.research@umassmed.edu.