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Lymphoma Research and Clinical Trials

Discovering and Delivering Compassionate, Coordinated Care

At UMass Memorial Cancer Center of Excellence in Worcester, MA, we work in partnership with the University of Massachusetts Medical School to research new treatments for cancer. UMass Memorial is at the forefront of some of the nation’s most promising research and treatment programs. Through our Cancer Center Clinical Research Office (CRO), we perform breakthrough research and clinical trials to improve treatment and your quality of life. 

 

Lymphoma Trials Underway

The University of Nebraska Medical Center
A Phase II Study of Cyclophosphamide, Etoposide, Vincristine and Prednisone (CEOP) Alternating With Pralatrexate (P) As Front Line Therapy For Patients With Stage Ii, Iii And IV Peripheral T-Cell Non-Hodgkin’s Lymphoma
INVESTIGATOR:  Andy Evens, DO, MSc
SPONSOR:  The University of Nebraska Medical Center
Combined Study at clinicaltrials.gov

ECOG E2408
A 3-Arm Randomized Phase II Trial of Bendamustine-Rituximab (BR) Followed by Rituximab vs Bortezomib-BR (BVR) Followed by Rituximab vs BR Followed by Lenalidomide/Rituximab in High Risk Follicular Lymphoma
INVESTIGATOR:  Andy Evens, DO, MSc
SPONSOR:  Eastern Cooperative Oncology Group (ECOG)
ECOG E2408 at clinicaltrials.gov

SWOG 0816
A phase 2 trial of response-adapted therapy of stage III-IV Hodgkin lymphoma using early interim FDG-PET imaging
INVESTIGATOR:  Andy Evens, DO, MSc
SPONSOR:  NCI/Southwest Oncology Group
SWOG 0816 at clinicaltrials.gov

CALGB 50604
A Phase II Trial of Response-adapted Chemotherapy Based on Positron Emission Tomography for Non-bulky Stage I and II Hodgkin Lymphoma
INVESTIGATOR:  Andy Evens, DO, Msc
SPONSOR:  CALGB (Cancer And Leukemia Group B)
CALGB 50604 at clinicaltrials.gov

Northwestern University
Protocol NU11H01: A phase II trial of sequential SGN35 therapy with Adriamycin, vinblastine, and dacarbazine (S-AVD) for older patients with untreated Hodgkin lymphoma
INVESTIGATOR:  Andrew Evens, DO, MSc
SPONSOR:  Northwestern University
Northwestern University at clinicaltrials.gov

Spectrum Pharmaceuticals, Inc
SPI-MGD-11-201: A Randomized, Open-Label, Multi-Center, Phase 2 Study of Zevalin (ibritumomab tiuxetan) versus Zevalin and motexafin gadolinium in Patients with Rituximab-Refractory Low-grade or Follicular B-cell Non-Hodgkin’s Lymphoma
INVESTIGATOR:  Andrew Evens, DO, MSc
SPONSOR:  Spectrum Pharmaceuticals, Inc
Spectrum Pharmaceuticals at clinicaltrials.gov

 

Learn more about research and other clinical trials underway at the UMass Memorial Cancer Center of Excellence. 

To learn more about clinical trials and cancer research, call 508-856-3216 or email cancer.research@umassmed.edu.