Clinical Trials

  • Effect of Intravenous Alpha-1 Antitrypsin on Preserving Beta-cell Function in New-onset Type 1 Diabetes Mellitus (NIAID) (not yet recruiting)
  • A Phase III, 3-Arm, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Impact of Diamyd® on the Progression of Diabetes in Patients Newly Diagnosed with Type 1 Diabetes Mellitus (Diamyd Therapeutics AB)
  • TRX4 Therapeutic Evaluation of Different Multi-Dose Regimens in Type 1 Diabetes Mellitus (TTEDD) (Tolerx, Inc.)
  • DEFEND-1: Durable-Response Therapy Evaluation for Early- or New-Onset Type 1 Diabetes (Tolerx, Inc.) (closed, recruitment complete)
  • TrialNet Natural History Study of the Development of Type 1 Diabetes: (NIDDK)
  • TrialNet Oral Insulin Study for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus: (NIDDK)
  • PETS-DM Study: Teaching Parents of Newly Diagnosed Young Children with Type 1 Diabetes Management using a High Fidelity (Robotic) Patient Simulator (NINR)
  • Glycemic Control in Children and Adolescents with Double Diabetes: Trial of Optimized Insulin - Metformin Regimen (Novonordisk)
  • Feasibility of a Lifestyle Intervention in Adolescent Girls with the Metabolic Syndrome Study (Meyers) (recruiting only controls)
  • Vitamin D Study (FDSP)
  • Sibling Support of Pediatric Diabetes Self-Management: (NIDDK)
  • Protocol MS316: Recombinant Human Growth Hormone (rhGH) and Recombinant Human Insulin-Like Growth Factor-1 (rhIGF-1) Combination Therapy in Children with Short Stature Associated with IGF-1 Deficiency: A Three-year, Randomized, Multicenter, Open-label, Parallel-group, Active Treatment Controlled, Dose Selection Trial (Tercica, Inc.)
  • Voiding Dysfunction in Children with Diabetes
  • The Role of Adipose Inflammation in the Metabolic Sequelae associated with Childhood Obesity
  • The Role of Peripheral Mononuclear Cells in the Metabolic Sequelae associated with Early Obesity
  • Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study (NIH)