Big Advances for Little Hearts

This article originally appeared in Pathways, a magazine published for physicians and the community by UMass Memorial Medical Center.

"When I was growing up in the 1970s, there was no echocardiography available to detect congenital heart disease," said Darshak Sanghavi, MD, a pediatric cardiologist at UMass Memorial Children's Medical Center. "The doctor used a stethoscope and, perhaps, could detect a leaking valve by listening to the heart. And he usually only found that if a child presented with breathing difficulty.

"But with today's diagnostic imaging technology, we can know if there are congenital heart defects before there are symptoms," he continued. "With fetal echocardiography, we can even know about problems before a child is born."

The technological advances in cardiac imaging for pediatric patients are helping to address a significant health problem. According to the American Heart Association, an estimated 35,000 babies in the United States - eight out of every 1,000 - are born with a heart defect each year. This makes congenital heart defects the most common birth defect and the number-one cause of death from birth defects during the first year of life. Sadly, many newborns with major congenital heart defects are diagnosed at autopsy, Dr. Sanghavi noted. "But it is our hope that these imaging advances can help save these children," he added.

To that end, the UMass Memorial Children's Medical Center Division of Pediatric Cardiology has made a significant investment in cardiac imaging technology - including fetal echocardiography, transthoracic echocardiography and cardiac MRI -as well as talent.

The Children's Medical Center is committed to providing the highest-quality diagnostic imaging available today. As proof of this commitment, the division recently transferred its imaging systems to a fully digital platform, an upgrade that translates into improved data flow and efficiency - which also yields benefits for referring physicians.

"By digitizing the entire medical record, we can send information to a referring physician with a single click," said Dr. Sanghavi. "Plus, our notes are electronically dictated and transcribed, so we can fax reports to referring physicians quickly and easily. It definitely helps to improve communication."

The data and image management capabilities of the digital system also enhance clinical care. "In imaging a child's heart with echo, we look at 50 to 60 different structures," explained Dr. Sanghavi. "This is a huge amount of data compared to imaging an adult heart. In the past, these studies were stored on VHS videotape and, once completed, had to be stored off-site since they required so much space. When you needed to view a previous study, retrieving it consumed valuable time.

"Now, the digital studies are stored on a server and instantly available," he continued. "I can call up previous studies and reports from my office, the NICU, at home - anywhere a high-speed Internet connection is available. This kind of access to information is invaluable for timely clinical decision-making."

Similarly, digital images can be transferred quickly between specialists at the UMass Memorial Children's Medical Center in Worcester and Children's Hospital in Boston, where pediatric patients who require cardiac catheterization or surgery are transferred for this segment of their treatment. The team works closely with surgical and interventional cardiologists at Children's, and the digital capabilities the two to share information seamlessly.

It is in the area of image quality, however, that the new digital technology arguably confers the greatest benefits.

"Most congenital heart disease treatment depends on accurate images of what's going on, and seeing it clearly at various points in time," Dr. Sanghavi stated. "But children are not just little adults; imaging their hearts requires special equipment and higher-frequency ultrasound probes. A 400-gram infant in the NICU has a heart the size of a cherry tomato that cannot be visualized with an adult probe. Fortunately, companies today have developed diagnostic equipment specifically for these smaller bodies. And they deliver crystal-clear pictures, enhanced even further by digital technology.

"Fetal echo gives us complete pictures of the heart and the ability to define blood flow patterns at 19 to 22 weeks," he continued. "This enables parents and their doctors to plan deliveries better and, in the case of some rhythm disturbances, to medically intervene while the fetus is in utero and cure the child without surgery."

As children grow, it becomes increasingly difficult to visualize their hearts using echocardiography. Cardiac MRI has become an essential imaging modality to assess cardiac function and vascular anatomy. It enables the team to easily visualize the intracardiac anatomy and thoracic vessels in older children and young adults with a clarity that surpasses that of echocardiography."

"It's hard to overstate just how much the diagnosis and treatment of congenital heart disease have improved in the last 20 to 30 years as a result of these advances," Dr. Sanghavi added.

Having advanced pediatric imaging capabilities available in this region is a big plus for community pediatricians as well. "To have these imaging capabilities available right here in the local community is wonderful," said Lynda Young, MD, a pediatrician in private practice in Worcester for more than 30 years. "It speeds diagnosis and our ability to make decisions about what we can do for the patient.

"And to have the personal contact with these specialists means a great deal," she continued, referring to the cardiology team. "They're excellent about keeping me informed when they see one of my patients. I always get a call at the time the patient is seen and receive a timely follow-up referral letter, so I know their thoughts and what to tell my patient's parents.

"And they're easy to access," Dr. Young added. "You don't have to wait six months for an appointment. They're available on an emergency basis, too."

"We're here in the clinic four days a week for both pediatric outpatients and fetal consultations," Dr. Sanghavi noted. "We welcome the opportunity to see patients for an evaluation so that we can help referring physicians determine the most appropriate tests and imaging parameters to address a specific problem."

From fetal echo to assessment at birth, in the NICU, and through childhood and adolescence, the team is fully outfitted to care for pediatric patients with congenital heart disease