Cervical Cancer

Screening is Key to Battling Silent Killer

This article originally appeared in invision, a magazine published for staff at UMass Memorial Medical Center.

"An ounce of prevention is worth a pound of cure" certainly holds true when it comes to cervical cancer.

Although uncommon, cervical cancer afflicts 14,000 women and causes 5,000 deaths in the United States annually. However, almost 60 percent of these cases can be prevented with regular screenings.

Cervical cancer is caused by the human papillomavirus (HPV), the same virus that produces genital warts. There are more than 100 strains of HPV, and some types can lead to cervical cancer. HPV is a very common, sexually transmitted virus that almost all women contract at some point in their lifetime. Most cases are cleared by the body's immune system. However, persistent HPV can generate abnormal cell growth that if left untreated, may lead to cervical cancer.

Cervical cancer most often affects women in their 30s through 50s, especially those who do not have regular PAP smears to identify abnormal cells. It is a silent killer because there are seldom symptoms until the disease has progressed to an advanced stage. Men also contract HPV and can infect their partners; however, male (penile) cancer caused by the virus is very rare.

The good news is that if found early, cervical cancer is curable in 85 to 90 percent of cases. If detected in advanced stages, survival rates drop to 15 to 25 percent. Current treatments include radical hysterectomy or radiation therapy, with chemotherapy added for advanced cases.

The Food and Drug Administration recently approved a new vaccine to prevent certain types of HPV. However, the best line of defense for cervical cancer is regular screenings. "Women need to be educated about HPV. They need to talk with their doctors and have regular screenings," advised gynecologic oncologist Susan Zweizig, MD.